ISPRED4: Interaction Sites PREDiction in protein structures with a refining grammar model
نویسندگان
چکیده
منابع مشابه
Prediction of Protein–Protein Interaction Sites in Sequences and 3D Structures by Random Forests
Identifying interaction sites in proteins provides important clues to the function of a protein and is becoming increasingly relevant in topics such as systems biology and drug discovery. Although there are numerous papers on the prediction of interaction sites using information derived from structure, there are only a few case reports on the prediction of interaction residues based solely on p...
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Protein-protein interactions play a crucial role in many biological processes such as immune response, enzyme catalysis, and signal transduction. Identifying the interacting sites between the proteins is important for understanding the functional mechanisms, and is crucial for drug development. Interaction profile hidden Markov model (ipHMM) was shown to be an effective tool for modeling protei...
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ژورنال
عنوان ژورنال: Bioinformatics
سال: 2017
ISSN: 1367-4803,1460-2059
DOI: 10.1093/bioinformatics/btx044